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Esta diversidad estructural permite una gama de opciones teraputicas con perfiles de eficacia y tolerabilidad distintos

ATP-citrate lyase (ACLY) catalyzes the reaction of cytoplasmic citrate with coenzyme A (CoA) to form oxaloacetate and acetyl-CoA

The efficacy and toxicity of hydroquinone are contingent on its final concentration, the vehicle that hydroquinone is in and the chemical stability of the product

Similarly, in DLB, neuroinflammation due to the lack of SCFAs is mitigated in the substantia nigra but not in the cortex by secondary bile acids generated by the increased abundance of Ruminococcus torques and Collinsella 80

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